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Systematic Reviews

Systematic Reviews & Meta-analysis

OXON performs systematic reviews and meta-analyses to inform healthcare decisions and policies

Advances in methodology and creation of standards have improved the reliability and consistency of these syntheses of research findings.

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SYSTEMATIC REVIEWS

OXON conducts systematic reviews of epidemiological, registry, safety, PRO, health economic and trial data. Often we proceed to synthesise these data using meta-analysis. However, a qualitative systematic review is conducted where meta-analysis is not possible or appropriate.

We use the standardised methodology of Cochrane for trial evidence and diverse alternative methodologies for non-experimental evidence.

Cochrane Database of Systematic Reviews

META-ANALISYS

OXON conducts systematic reviews and meta-analysis of epidemiological, registry, safety, PRO, health economic and trial data to support:

• Prevalence estimates for orphan drug applications
• Submission of drugs during the integrated safety summary in the Common Technical Document (CTD)
• Disease models
• Evidence-based decision-making
• Combination of data from different patient registries
• Direct and indirect meta-analyses to support cost-effectiveness models
• Aggregated and individual-person data meta-analysis.

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